In a breakthrough research researchers have developed a fertility wand, which has been shown to twice the chances of getting pregnant. The rates of pregnancy in women undergoing IVF using the new treatment was thirty-three percent in comparison to fourteen percent in group that did not used the new therapy.
The new treatment works on the lining of the womb. According to fertility experts a poor quality of womb lining could be significant aspect in women struggling to conceive. In existing treatment, a fertilised egg or embryo has to be implanted into the womb lining for a woman to get pregnant.
But this is complex process, involving hormones, growth factors and chemicals made by the immune system known as cytokines. There is no treatment after it if this treatment goes wrong. However, new invention by Israeli researchers showed that slight harm to womb lining resulted in improved fertility.
The treatment involves inserting a long plastic tube-like apparatus known by the name of Pipelle, into the womb and then rotating it 360 degrees to scuff the womb lining. Patients are given painkiller thirty minutes prior to the procedure that is carried out two times in one month.
Researchers carried out a new trial involving one hundred women those previously failed to conceive with IVF treatment, despite their embryos being of good quality. These women were given the new treatment or were assigned in a control group. The results showed that pregnancy rates in treated group were more than twice compared to control group.
A gynecologist Sanjay Vyas from Southmead Hospital, Bristol, while commenting on the study says, this is very exciting work. Implantation failure when the quality of embryos transferred is good can be distressing as it cannot be predicted. This intercession is simple, and if it genuinely improves the implantation rate, it would be very good news.
The study findings were published in the Journal of Human Reproduction Sciences. More clinical trials using the same technique are now underway. A US study found this damage triggered a repair reaction in the body, producing growth factors and cytokines. It also increased the activity of genes believed to play a role in preparing the lining for implantation.