Preventing asthma with the help of vaccine-like jabs is being studied by researchers from Switzerland subsequent to mice study, in which they found that contaminations can block the growth of disease in mice. The research team led by Prof Anne Muller from the University of Zurich premeditated the effect of bacterial infection on asthma-like symptoms in mice.
The study showed that Helicobacter pylori infection cared for mice from allergen-induced asthma like tissue inflammation and airway hyper-responsiveness.Another study conducted by researchers from Stanford University School of Medicine in California revealed that the immune molecule gamma-interferon is also associated with to the growth of asthma.
The researchers again made use of mice to observe the effect of asthma-like symptoms. They believe their findings could escort to the development of new drug treatments for the condition. Prof Muller stated that they are working on a vaccine like jab with the aim of aggressively tolerating the host to the bacteria.
She added it would make the immune system tolerant of H pylor0 infections and perhaps cross-tolerant of other antigens, including allergens. This approach would most surely need a first shot followed by multiple boosts using fragments or subunit vaccine, rather than live bacteria.
Her study also suggested that any needless use of antibiotics during childhood should be avoided. To preserve aboriginal micro biota that may churn out to be beneficial not only in the situation of allergies, but also of other chronic inflammatory or autoimmune diseases, added Prof Muller.