DNA disease kits claim to predict life-threatening ailments should be banned

By Rajan | Tuesday, May 31st, 2011
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In novel study researchers allege that mail-order kits which claim to envisage your odds of developing life-threatening diseases are imprecise and should be prohibited. The most expensive test perceives clients dispatch DNA samples which are then analyzed to gauge how a person having risk of developing several illnesses compares with the average.

The statistics from one lakh people was simulated in a study that used formulas provided by hereditary testing firm deCODEme from US and Iceland to acquire the threat of developing eight common ailments including prostate cancer and diabetes. A large part of population was rates as having raised risk of each ailment.

Even probability of developing the diseases was not much higher than for an average subject. The first autonomous study to observe the kits states that the information they generate is of little meaningful benefit and in several cases, plain wrong.

According to study author Prof Cecile Janssens from the Erasmus University Medical Centre in Rotterdam, Holland, in many cases the dissimilarity in ailment risk is too small to be of relevance. The tests only take genetic factors into account, ignoring other variables like diet, environment and lifestyle.

A separate analysis of geneticists from twenty-eight countries revealed that two-third of them wanted to ban the tests, stating people should not be left to interpret the results themselves without the help of a doctor. It raises further qualms that in five out of eight diseases calculated by deCODEme, some people had risks higher than one hundred percent.

The firm takes widespread measures both to provide accuracy and to emphasize the context for relevance at all steps in the process of analyzing and presenting statistics, stated Brian Naughton, product manager for 23andMe.


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