Memory booster pill could cure elderly cognitive impairment

By Rajan | Thursday, October 14th, 2010
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The British researchers have developed a pill that could prevent so called senior moments. The pill is designed mainly for forgetfulness rather than brain disease and has already tested on animals. By taking the drug later in life could end the misery of not being able to remembering the names or forgetting where the car keys are.

About a third elderly suffered from meek cognitive impairment. But this impairment is a key risk aspect for Alzheimer’s disease, explained lead researcher Jonathan Seckl from Edinburgh University. It is quiet annoying if you cannot remember where you put your keys or what you left the house to do.

Such problems are as a minimum partly due to higher level of stress hormones, including cortisol that damages memory hub of the brain. In a study lead researcher Professor Seckl has revealed that an enzymes known as 11 beta-HSD1, enhances levels of cortisol and he made the pill to halt that episode.

In a lab trail, they have shown that the pill called UOe1961 had sharpened the minds of elderly mice to such a degree that they were equivalent to much younger mice at performing tests of memory and learning. The animals were coming toward the end of their lifespan and had profound deficits in their ability to learn things.

Researchers turned them back equal to young a mouse which was very thrilling. It taught them that sort of memory loss is not irretrievable. Moreover the animals were treated only for two weeks, reported the study published in the Journal of Neuroscience. It is too early to recognize the side-effects of UOE1961.

To reduce levels of stress hormones is likely to be good for the heart. It could go to human trials next year and if these are successful, be on the market within five years.


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