Ketamine works like magic drug for depression

By Rajan | Saturday, August 21st, 2010
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According to latest research Ketamine also called Special K works like magic to ease depression. The drug rapidly persuades the renewal of synaptic links between nerve cells in the brain. Researchers think that by understanding the way how drugs works could escort to improved anti-depressed treatment.

The latest studies have shown that patients suffering from depression and resisted all other treatments get improvement with hours after getting katamine. Katamine has to be administered intravenously to toil as antidepressant because the drug is not a handy therapy. Its use can cause short- range of psychotic symptoms.

Presently about forty percent of patients of depression do not respond to medication. But researchers claimed that ketamine could work as a steer to vastly hopeful new treatments for depression. It is like a magic drug and one dose of it can work quickly and its effects last for seven days, said Professor Ronald Duman, a psychiatrist from Yale University in the US.

Katamine causes psychosomatic dependence and leave users susceptible and powerless. It has disreputable repute as a date rape drug. The antidepressant qualities of ketamine have been tinted in clinical trials in US ten years ago. The different studies have shown that nearly seventy percent of depressed patient respond well within hours after injecting ketamine.

A team of researchers led by Prof Duman recorded the molecular action of the drug on the brains of mice. It was found that keatmine acted on an alleyway that quickly forms new association between neurons, process known as synaptogenesis.

Understanding the mechanism essential for antidepressant affects of ketamine permit to aim at the problem at a diversity of potential sites within that alleyway, said Professor George Aghajanian, co-author from Yale School of Medicine. Moreover keatmine has also been shown speedily prevent suicidal thoughts. This benefit was not usually seen in conventional antidepressants


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